This page provides additional material to the scientific article "Loss of G-A base pairs is insufficient for achieving a large opening of U4 snRNA K-turn motif" published by Vlad Cojocaru, Reinhard Klement, and Thomas Jovin in Nucleic Acids Research, 2005, vol. 33, issue 10, pp. 3435-3446


Cover of Nucleic Acids Research, 2005, vol. 33, issue 10


The three LES-MD trajectories of the unbound Kt-U4 RNA (LES1, LES2, and LES4) described in detail in the paper are shown here as MPEG movies. The trajectories are shown for one of the 4 copies/region ( the other 3 copies follow the same trajectory).


The LES4 trajectory of the unbound Kt-U4 (10 ns)


The LES1 trajectory of the unbound Kt-U4 (10 ns)


The LES2 trajectory of the unbound Kt-U4 (10 ns)


The RNA backbone is represented as grey tube, while the bases are colored according to the residue names: adenines in red, guanines in blues, cytosines in orange, and uracils in yellow. In CPK representation, oxygens are shown in pink and nitrogens in cyan. Hydrogen bonds are shown in dotted black lines.


Note: The material presented here is only to be used complementary to the research article mentioned above. For any additional information please send an e-mail to the address below or contact the corresponding author (as mentioned in the paper)


Vlad.Cojocaru@eml-r.villa-bosch.de


16.11.2005 - Vlad Cojocaru