ELSA |
ELEKTRONISCHER STOFFWECHSEL-ATLAS |
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ELSA stands for ELEKTRONISCHER STOFFWECHSEL-ATLAS. It was funded by the BMBF and the Klaus Tschira Foundation (KTS) as a collaboration between research groups and companies comprising experts in genetics, biochemistry, bioinformatics and computer science. (Start: June 01, 1999 - End: December 2002) The goal of the ELSA project was the development of methods to support the modeling and simulation of biochemical pathways. The project had as case study Mycoplasma pneumoniae, an organism which has been experimentally analyzed in great detail by one of the project partners (ZMBH). A comparative analysis of genome and protein sequences received from sequencing projects played an essential role in ELSA, together with the integration of heterogeneous data from existing databases, the retrieval of experimental data and the computational modeling of pathways. Complementing the methods developed were a series of applications and tools to allow both experimentalists and theoreticians to gain a deeper insight into biochemical pathways. |